(S)-Laudanosine

CAS 2688-77-9 MFCD02688779

化学结构图

2688-77-9
SMILES: COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2C)cc1OC

化学属性

Mol. Weight357
Mol. FormulaC21H27NO4

别名和识别编码

CAS Number2688-77-9
Chemical Name(S)-Laudanosine
Synonym (1S)- laudanosine
Chemical Name Translation
PubChem Substance ID73397
InChIInChI=1S/C21H27NO4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17H,8-10H2,1-5H3/t17-/m0/s1
MDL Number
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分类

  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cau

相关文献及参考

  • Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986),
  • Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992),
  • Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),

系列性分类

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