8-Bromoadenosine 8-溴膘苷

CAS 2946-39-6 MFCD00005733

化学结构图

2946-39-6
SMILES: Nc1ncnc2c1nc(Br)n2C1OC(CO)C(O)C1O

化学属性

Mol. FormulaC10H12BrN5O4
Mol. Weight346.14
Density1.422
Melting Point210-212°C
TSCANo
Stability对空气敏感
Appearance powder
Boiling Point717.7°C at 760 mmHg

别名和识别编码

Chemical Name8-Bromoadenosine
CAS Number2946-39-6
Synonym 8-Bromoadenosine {LY} 8-Bromoadenosine {} {LY} 8-Bromoadenosine {} {} {LY} 8-Bromoadenosine {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 8-Bromoadenosine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number220-959-0
Beilstein Registry Number627737
MDL NumberMFCD00005733
PubChem Substance ID96544
Chemical Name Translation8-溴膘苷
InChIKeyVJUPMOPLUQHMLE-UUOKFMHZSA-N
LabNetwork Molecule IDLN00201591
InChIInChI=1S/C10H12BrN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
Canonical SMILESO[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@@H]1CO
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分类

  • Bases & Related Reagents
  • {SNA} Nucleoside Analogs, 核苷，核苷酸和寡核苷酸, 生化试剂
  • Nucleotides
  • {SNA} B, Bioactive Small Molecule Alphabetical Index, Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides, 生物活性小分子, 细胞生物学
  • {SNA} Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nu

产品应用

  • Inhibits the binding of cyclic AMP and adenosine to the activated cyclic AMP/adenosine binding protein

相关文献及参考

  • Dang, Q., et al.: J. Med. Chem., 52, 2880 (2009),
  • Du, J., et al.: Biochem., 48, 2878 (2009),
  • Adenosine binding inhibitor.

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light Air Sensitive {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {}
Hazard Codes Xi

其他信息

  • Alfa Aesar:8-溴腺苷,98% 8-Bromoadenosine, 98%(2946-39-6)
  • Acros Organics:8-Bromoadenosine, 98%(2946-39-6)
  • 8-溴膘苷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 155780050 8-溴膘苷 8-Bromoadenosine 98% 5 GR 4998元 2010/06/21 155780010 8-溴膘苷 8-Bromoadenosine 98% 1 GR 1445元 2010/06/21 155782500 8-溴膘苷 8-Bromoadenosine 98% 250 MG 590元
  • 敏感性:Air Sensitive
  • F:10-23
  • color:white
  • MOL 文件:2946-39-6.mol
  • Sigma Aldrich:2946-39-6(sigmaaldrich)

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Nucleoside Analogs - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Nucleosides, Nucleotides, Oligonucleotides - Biochemicals and Reagents
  4. Synthetic Oligonucleotides and Related Reagents - Nucleosides, Nucleotides, Oligonucleotides
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Nucleosides, Nucleotides, Oligonucleotides
  4. NAD and Analogs

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