Depramine

CAS 303-54-8 MFCD00865408

化学结构图

303-54-8
SMILES: CN(C)CCCN1c2ccccc2C=Cc2ccccc21

化学属性

Mol. FormulaC19H22N2
Mol. Weight278.43

别名和识别编码

Chemical Name5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-
Synonym 10,11-dehydroimipramine 10,11-dehydroimipramine fumarate (1:1) 10,11-dehydroimipramine fumarate (2:1) 10,11-dehydroimipramine hydrochloride 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine CIBA G-31406 depramine
Wiswesser Line NotationT C676 BNJ B3N1&1
CAS Number303-54-8
Beilstein Registry Number1319717
PubChem Substance ID67534
InChIInChI=1S/C19H22N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-13H,7,14-15H2,1-2H3
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安全信息

RTECSHO1480000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 41 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959

系列性分类

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