Pristinamycin IA DISCONTINUED

CAS 3131-03-1 MFCD N/A

化学结构图

3131-03-1
SMILES: CN(C)C1=CC=C(CC2C(=O)N3CCC(=O)C[C@@H]3C(=O)N[C@H](C3C=CC=CC=3)C(=O)O[C@@H](C)[C@@H](NC(=O)C3=NC=CC=C3O)C(=O)N[C@@H](CC)C(=O)N3CCC[C@@H]3C(=O)N2C)C=C1 |&1:17,21,31,33,47,56|

化学属性

Mol. Weight867.07
Mol. FormulaC45H54N8O10

别名和识别编码

CAS Number3131-03-1
Chemical NamePristinamycin IA DISCONTINUED
Synonym Ostreogrycin B Mikamycin IA Mikamycin B Pristinamycin IA Antibiotic PA 114 B1 Antibiotic PA 114B ######## Streptogramin B Antibiotic 899 PA 114B Vernamycin BA
Chemical Name Translation
Wiswesser Line NotationT F5-19-6 ANV DNV JNV MMV QOV TMV A&VTJ C1R DN1&1& D1L2 P1 SR& OMV- BT6NJ CQ
Beilstein Registry Number0078387
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分类

  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • One of the two major components of Pristinamycin (Pristinamycin IA and Pristinamycin IIA (or Virginiamycin M1-V673810).

相关文献及参考

  • Crooy, P., et al.: J. Antibiot., 25, 371 (1972),
  • Allington, D., et al.: Clin. Therap., 23, 24 (2001),
  • Eeman, M., et al.: Langmuir, 22, 11337 (2006),

安全信息

RTECSZA4870000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,750,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,367,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,750,1967

系列性分类

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