Trimipramine

CAS 3564-66-7 MFCD N/A

化学结构图

3564-66-7
SMILES: CC(CN(C)C)CN1c2ccccc2CCc2ccccc21

化学属性

Mol. FormulaC20H26N2
Mol. Weight294.48

别名和识别编码

Synonym 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine 5H-Dibenz(b,f)azepine, Apo Trimip Apo-Trimip ApoTrimip Eldoral Herphonal Novo Tripramine Novo-Tripramine NovoTripramine Nu Trimipramine Nu-Trimipramine NuTrimipramine Rhotrimine Stangyl Surmontil Surmontil Maleate Trimeprimine Trimidura Trimineurin Trimineurin Maleate Trimipramin AZU Trimipramin Stada Trimipramin beta Trimipramin neurazpharm Trimipramin-neurazpharm Trimipramine Trimipramine Maleate Trimipramine Maleate (1:1) Trimipramine Maleate (1:1), (+)-Isomer Trimipramine Maleate (1:1), (+-)-Isomer Trimipramine Maleate (1:1), (-)-Isomer Trimipramine Mesyla
Chemical Name5H-Dibenz(b,f)azepine,5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-,(+)-
CAS Number3564-66-7
Beilstein Registry Number1321466
PubChem Substance ID5584
InChIInChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3
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安全信息

RTECSHO1230000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 415 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 155,307,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 155,307,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 155,307,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 395 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)

Hazard statements
  • H301 Toxic if swallowed 吞食有毒
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P301+P310
  • P301+P316
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

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