Ethylamine, N,N-dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)-, hydrochloride 2-[(RS)-(4-METHYLPHENYL)

CAS 4024-34-4 MFCD00550569

化学结构图

4024-34-4
SMILES: Cc1ccc(C(OCC[NH+](C)C)c2ccccc2)cc1.[Cl-]

化学属性

Mol. Weight305.88
Mol. FormulaC18H24ClNO

别名和识别编码

Wiswesser Line Notation1N1&2OYR&R D1 &GH
Chemical NamePHENYLMETHOXY]-N,N,DIMETHYLETHANAMINE HYDROCHLORIDE (Diphenhydramine Impurity B) Pharmaceutical Secondary Standard; Certified Reference Material 2-?[(RS)?-?(4-?Methylphenyl)?phenylmethoxy]?-?N,?N-?dimethylethanamine Hydrochloride
Synonym N,N-Dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)ethylamine hydrochloride Ethylamine, N,N-dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)-, N,N-Dimethyl-2-(alpha-(p-tolyl)benzyloxy)ethylamine hydrochloride
CAS Number4024-34-4
Chemical Name Translation2-[(RS)-(4-METHYLPHENYL)
Chemicalbook IDCB2918084
PubChem Substance ID19934
InChIInChI=1S/C18H23NO.ClH/c1-15-9-11-17(12-10-15)18(20-14-13-19(2)3)16-7-5-4-6-8-16;/h4-12,18H,13-14H2,1-3H3;1H
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安全信息

RTECSKR6706600
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 112,318,1954

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 3,272,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,964,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,964,1964

Hazard statements
  • H302 Harmful if swallowed 吞食有害
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P312
  • P330 Rinse mouth. 漱口
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类


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