Beclomethasone 倍氯米松溶液

CAS 4419-39-0 MFCD00135614

化学结构图

4419-39-0
SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

化学属性

Mol. FormulaC22H29ClO5
Mol. Weight408.92
Melting Point198
Stability对光敏感

别名和识别编码

Chemical NameBeclomethasone
CAS Number4419-39-0
Synonym (11,16)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (11?,16?)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9-Chloro-11beta,17,21-trihydroxy-16beta-methyl-pregna-1,4-diene-3,20-dione 9?-Chloro-16?-methylprednisolone 9ALPHA-CHLORO-16BETA-METHYL-1,4-PREGNADIENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpr 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 9α-Chloro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione BECLOMETHASONE Beclometasone Beclomethasone (base and/or unspecified salts) Beclomethasone Dipropionate 5534-09-8 /Base {} {
MDL NumberMFCD00135614
PubChem Substance ID20469
EC Number224-585-9
Chemical Name Translation倍氯米松溶液
Merck Number13,1020
LabNetwork Molecule IDLN00194291
InChIInChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
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分类

  • {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Cell Signaling and Neuroscience, GlaxoSmithKline, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, 细胞生物学
  • {SNA} Approved Therapeutics/Drug Candidates, B, GlaxoSmithKline, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, GlaxoSmithKline, Immune Cell Signal

产品应用

  • 校准仪器和装置；评价方法；工作标准；质量保证/质量控制

相关文献及参考

  • Brogden, R.N., et al.: Drugs, 28, 99 (1984),
  • Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982),
  • Rao, M., et al.: J. Asthma, 19, 21 (1982),
  • Small, P., et al.: Ann. Allergy, 49, 127 (1982),
  • [1]. He S, et al. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 储存温度2-8°C 2-8°C
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

其他信息

  • 方法一:由地塞米松制得。
  • 用途一:制取倍氯米松二丙酸酯。
  • Sigma Aldrich:4419-39-0(sigmaaldrich)
  • MOL 文件:4419-39-0.mol
  • 上游原料:地塞米松

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Approved Therapeutics/Drug Candidates - Cell Signaling and Neuroscience
  5. GlaxoSmithKline - Approved Therapeutics/Drug Candidates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Immune Cell Signaling and Blood - Cell Signaling and Neuroscience
  5. Immune System Regulation - Immune Cell Signaling and Blood
  6. Immunomodulators and Antibiotics - Immune System Regulation
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Glucocorticoid Receptor  (糖皮质激素受体)

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