Atropine

CAS 4438-22-6 MFCD N/A

化学结构图

4438-22-6
SMILES: CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2

化学属性

Mol. Weight305.41
Mol. FormulaC17H23NO4

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, (+-)-tropate(ester), 8-oxide
Chemicalbook IDCB01178061
Synonym Genatropine Aminoxytropine tropate Genatropin Atropine N-oxide Atropine oxide
CAS Number4438-22-6
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安全信息

RTECSYM6105000
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,513,1948

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RDMU** "Vergleichende Untersuchungen uber Genatropin und Atropin,
   Dissertation," Rathscheck, U., Pharmakologischen Institut der Westfalichen
   Wilhelms-Universitat Muenster/Westf., Fed. Rep. Ger., 1934
   Volume(issue)/page/year: -,-,1934

系列性分类


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