Salicylic acid, 4-amino-, 2-(diethylamino)ethyl ester 羟普鲁卡因

CAS 487-53-6 MFCD00047845

化学结构图

487-53-6
SMILES: CCN(CC)CCOC(=O)c1ccc(N)cc1O

化学属性

Mol. FormulaC13H20N2O3
Mol. Weight252.35

别名和识别编码

Chemical NameSalicylic acid, 4-amino-, 2-(diethylamino)ethyl ester
Wiswesser Line NotationZR CQ DVO2N2&2
Synonym Oxycaine Diethylaminoethanol p-aminosalicylate 2-Diethylaminoethyl 4-aminosalicylate Diethylaminoethyl-3-hydroxy-4-aminobenzoate Metahydroxyprocaine Diethylaminoethyl p-aminosalicylate m-Hydroxyprocaine 2-Diethylaminoethyl p-aminosalicylate Oxyprocaine Oxyprocain Benzoic acid, p-amino-m-hydroxy-, 2-(diethylamino)ethyl ester Hydroxyprocaine
CAS Number487-53-6
Beilstein Registry Number2650192
Chemical Name Translation羟普鲁卡因
MDL Number
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安全信息

RTECSVO1575000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KLWOAZ Klinische Wochenscrift.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1922-  Volume(issue)/page/year:
   31,97,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 2,112,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 10,284,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KLWOAZ Klinische Wochenscrift.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1922-  Volume(issue)/page/year:
   31,97

系列性分类


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