(7R,7aR,14R,14aS)-Dodecahydro-2H,6H-7,14-Methanodipyrido[1,2-A:1’,2’-E][1,5]Diazocine (7R,7aR,14R,14aS)-十四氢-7,14-甲桥二吡啶并[1,2-a:1’,2’-e][1,5]氮杂环辛烷

CAS 492-08-0 MFCD00869353

化学结构图

492-08-0
SMILES: C1CCN2C[C@H]3C[C@H](CN4CCCC[C@H]34)[C@@H]2C1

化学属性

Mol. FormulaC15H26N2
Mol. Weight234.39
Refractive index1.5260 to 1.5300
Boiling Point174°C/8mmHg(lit.)
Density1.02
Melting Point201

别名和识别编码

Chemical Name(7R,7aR,14R,14aS)-Dodecahydro-2H,6H-7,14-Methanodipyrido[1,2-A:1’,2’-E][1,5]Diazocine
CAS Number492-08-0
Reaxys-RN82448
MDL NumberMFCD00869353
Synonym Pachycarpine d-Sparteine 鹰爪豆碱
Chemical Name Translation(7R,7aR,14R,14aS)-十四氢-7,14-甲桥二吡啶并[1,2-a:1’,2’-e][1,5]氮杂环辛烷
PubChem Substance ID160871001
InChIKeySLRCCWJSBJZJBV-TUVASFSCSA-N
Wiswesser Line NotationT C66 K66 A HN PNTJ
Beilstein Registry Number3540601
LabNetwork Molecule IDLN00347070
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安全信息

RTECSRT0620000
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P350
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
GHS Symbol
Storage condition 0-10°C
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 89100 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   SHIYDO Shaanxi Xinyiyao.  Shaanxi New Medical.  (Shaanxi Renmin Chubanshe,
   Xi'an, Shaanxi, Peop. Rep. China)  V.1-    1972-  Volume(issue)/page/year:
   11(6),53,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   32ZCAI "Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich,
   D.A., Moscow, First Moscow Medical Institute, 1967 Volume(issue)/page/year:
   -,175,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 21(5),46,1958

WGK Germany3

系列性分类


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