Aspirin sodium

CAS 493-53-8 MFCD N/A

化学结构图

493-53-8
SMILES: CC(=O)Oc1ccccc1C(=O)[O-].[Na+]

化学属性

Mol. FormulaC9H7O4.Na
Mol. Weight202.15

别名和识别编码

Chemical NameSalicylic acid, acetate, sodium salt
Chemicalbook IDCB3910353
Wiswesser Line NotationOVR BOV1 &-NA-
Synonym Aspirin-natrium O-Acetylsalicylic acid, sodium salt Sodium acetylsalicylate Acetylsalicylsaeure natriumsalz Acetylsalicylic acid sodium salt Sodium aspirin
CAS Number493-53-8
Chemical Name Translation
PubChem Substance ID23666729
InChIInChI=1S/C9H8O4.Na/c1-6(10)13-8-5-3-2-4-7(8)9(11)12;/h2-5H,1H3,(H,11,12);/q;+1/p-1
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安全信息

RTECSVO0875000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   79,357,1982

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G.,
   Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 
   Volume(issue)/page/year: -,-,1933

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 730 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 114,299,1955

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 909 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1290,1935

TYPE OF TEST            : TDLo - Lowest published t

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - rat Cells - not otherwise specified
DOSE/DURATION           : 300 mg/kg
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   24,219,1975

系列性分类

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