Rhapontigenin 丹叶大黄素

CAS 500-65-2 MFCD00017718

化学结构图

500-65-2
SMILES: COc1ccc(/C=C/c2cc(O)cc(O)c2)cc1O

化学属性

Mol. FormulaC15H14O4
Mol. Weight258.27
Melting Point189.0 to 193.0 deg-C

别名和识别编码

Chemical NameRhapontigenin
CAS Number500-65-2
Synonym (E)-5-[2-(3-Hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol rhapontigenin
Reaxys-RN2619492
PubChem Substance ID5320954
MDL NumberMFCD00017718
Chemical Name Translation丹叶大黄素
LabNetwork Molecule IDLN01320616
InChIInChI=1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
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相关文献及参考

  • [2]. Yeh YH, et al. Rhapontigenin inhibits TGF-β-mediated epithelial‑mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation.Oncol Rep. 2016 May;35(5):2887-95.
  • [3]. Park EK, et al. Antithrombotic and antiallergic activities of rhaponticin from Rhei Rhizoma are activated by human intestinal bacteria.Arch Pharm Res. 2002 Aug;25(4):528-33.
  • [1]. Roupe KA, et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies.J Pharm Pharm Sci. 2005 Aug 22;8(3):374-86.
  • [1]. Roupe KA, et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies.J Pharm Pharm Sci. 2005 Aug 22;8(3):374-86.
  • [2]. Yeh YH, et al. Rhapontigenin inhibits TGF-β-mediated epithelial‑mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation.O

安全信息

Storage condition 0-10 0-10°C

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Cytochrome P450  (细胞色素P450)

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