Pentetrazol 戊四唑

CAS 54-95-5 MFCD00005939

化学结构图

54-95-5
SMILES: C1CCc2nnnn2CC1

化学属性

Mol. FormulaC6H10N4
Mol. Weight138.17
Boiling Point194 °C/12 mmHg(lit.)
Melting Point59-61 °C(lit.)
TSCAYes
Flash Point194°C/12mm
Density1.73
Stability易吸潮
SolubilitySoluble in water (50 mg/ml), DMSO (100 mM), alcohol (1: <1), chloroform (1: <1), and methanol.

别名和识别编码

Chemical NamePentylenetetrazole
CAS Number54-95-5
Synonym ######## 1,2,3,3a-Tetrazacyclohepta-8a,2-cyclope 1,2,3,3a-Tetrazacyclohepta-8a,2-cyclopentadiene 1,5-PENTAMETHYLENE-1H-TETRAZOLE 1,5-PENTAMETHYLENETETRAZOLE 1,5-Pentamethylene-1H-tetrazole; 6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine 1,5-五亚甲基-1H-四唑 6,7,8,9-四氢-5H-四唑并氮杂卓 戊四唑 戊四氮 戊撑四唑 1,5-五亚甲基-1H-四唑;6,7,8,9 5-a)azepine,6,7,8,9-tetrahydro-5h-tetrazolo( 5H-Tetrazolo[1,5-a]azepine, 6,7,8,9-tetrahydro- 6,7,8,9-TETRAHYDRO-5H-TETR 6,7,8,9-TETRAHYDRO-5H-TETRAZOLO-[1,5-A]AZEPINE 6,7,8,9-Tetrahydro-5-azepotetrazole 6,7,8,9-Tetrahydro-5H-t 6,7,8,9-四氢-5H-四唑并氮杂卓 7,8,9,10-Tetrazabicyclo(5.3.0)-8,10-decadiene 7,8,9,10-Tetrazabicyclo[5.3.0]deca-8,10-diene 7,8,9,10-tetrazabicyclo( ALPHA,BETA-CYCLOPENTAMETHYLENETETRAZOLE {P
MDL NumberMFCD00005939
EC Number200-219-3
Merck Number14,7141
Beilstein Registry Number0135492
PubChem Substance ID5917
Chemical Name Translation戊四唑
Wiswesser Line NotationT57 ANNNN&TJ
LabNetwork Molecule IDLN00194882
InChIInChI=1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • Pharmaceuticals
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, P, Pharmacologicals, Stimulants
  • Heterocycles
  • Intermediates & Fine Chemicals
  • {SNA} Bioactive Small Molecule Alphabetical Index, Neurobiology, Neuroscience, P-PH, Pharmacologicals, Stimulants, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

产品应用

  • A useful biochemical in neurotransmitter studies.

相关文献及参考

  • Merck:14,7141
  • Goldenthal, et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),
  • Merck:14,7141 Beilstein: 26,II,213

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P316
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSXF8225000
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Packing GroupII
UN Number UN 2811 6.1/PG 3 2811 UN2811
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition -20°C 储存温度-20°C,充氩保存 2-8°C 储存 Hygroscopic
Hazard Codes T
Hazard Class6.1
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 6,583,1956

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - man
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 123,419,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 62 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   18,185,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal o

其他信息

  • 图谱信息:戊四唑(54-95-5)核磁图( 1 HNMR) 戊四唑(54-95-5)质谱(MS) 戊四唑(54-95-5)Raman光谱 戊四唑(54-95-5)红外图谱(IR1) 戊四唑(54-95-5)红外图谱(IR3) 戊四唑(54-95-5)核磁图( 13 CNMR) 戊四唑(54-95-5)红外图谱(IR2)
  • 易溶于水和乙醇。
  • 外观性质:白色结晶,微有辛辣苦味,易溶于水和乙醇。熔点:60 °C 沸点:194 °C
  • Sigma Aldrich:54-95-5(sigmaaldrich)
  • 用途一:非特定的早晚服用的兴奋剂,惊厥剂。
  • MSDS 信息:1,5-Pentamethylene-1H-tetrazole(54-95-5).msds
  • 敏感性:Hygroscopic
  • Alfa Aesar:1,5-五亚甲基-1H-四唑,98% 1,5-Pentamethylene-1H-tetrazole, 98%(54-95-5)
  • 戊四唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/05/25 L16185 1,5-五亚甲基-1H-四唑, 98% 1,5-Pentamethylene-1H-tetrazole, 98% 5g 175元 2010/05/25 L16185 1,5-五亚甲基-1H-四唑, 98% 1,5-Pentamethylene-1H-tetrazole, 98% 25g 407元
  • MOL 文件:54-95-5.mol
  • TCI Shanghai:1,5-五亚甲基四氮唑 1,5-Pentamethylenetetrazole,>;98.0%(GC)(54-95-5)

系列性分类


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