P,P-Bis(1-aziridinyl)-N-isopropylphosphinic amide

CAS 5774-35-6 MFCD01706508

化学结构图

5774-35-6
SMILES: CC(C)NP(=O)(N1CC1)N1CC1

化学属性

Mol. FormulaC7H16N3OP
Mol. Weight189.23

别名和识别编码

Chemical NamePhosphinic amide, P,P-bis(1-aziridinyl)-N-isopropyl-
InChIKeyANJZCRCYICVNEK-UHFFFAOYSA-N
Synonym P,P-Bis(1-aziridinyl)-N-isopropylaminophosphine oxide P,P-Bis(1-aziridinyl)-N-isopropylphosphinic amide ENT 51256 Phosphinic amide, P,P-bis(1-aziridinyl)-N-(1-methylethyl)-
CAS Number5774-35-6
PubChem Substance ID197048
InChIInChI=1S/C7H16N3OP/c1-7(2)8-12(11,9-3-4-9)10-5-6-10/h7H,3-6H2,1-2H3,(H,8,11)
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安全信息

RTECSSZ5828500 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 6 mmol/kg
REFERENCE :
   FOBLAN Folia Biologica (Prague).  (Academic Press Inc. Ltd., 24-28 Oval Rd.,
   London NW1 7DX, UK) V.1-    1955-  Volume(issue)/page/year: 20,1,1974

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2300 umol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 68,245,1971

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 ug/kg
REFERENCE :
   FOBLAN Folia Biologica (Prague).  (Academic Press Inc. Ltd., 24-28 Oval Rd.,
   London NW1 7DX, UK) V.1-    1955-  Volume(issue)/page/year: 20,1,1974

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 33 umol/L
REFERENCE :
   HEREAY Hereditas (Lund, Sweden).  (Gjoerloffsgatan 121, S-261 34 Landskrona,
   Sweden)  V.1-    1947-  Volume(issue)/page/year: 68,255,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   FOBLAN Folia Biologica (Prague).  (Academic Press Inc. Ltd., 24-28 Oval Rd.,
   London NW1 7DX, UK) V.1-    1955-  Volume(issue)/page/year: 20,1,1974

系列性分类

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