Guanethidine Sulfate 硫酸胍
CAS 60-02-6 MFCD00079332
化学结构图
SMILES: N=C(N)NCCN1CCCCCCC1.N=C(N)NCCN1CCCCCCC1.O=S(=O)(O)O
化学属性
| Mol. Formula | C10H22N4?1/2H2SO4 |
|---|---|
| Mol. Weight | 247 |
别名和识别编码
| Chemical Name | Guanethidine Sulfate |
|---|---|
| CAS Number | 60-02-6 |
| Synonym | Guanidine, (2-(octahydro-1-azocinyl)ethyl)-, sulfate (2:1) Ismelin sulfate Oktatenzin Sanotensin Iporal 胍乙啶半硫酸盐 Isobarin (2-(Hexahydro-1(2H)-azocinyl)ethyl)guanidine sulfate Guethine SU-5864 Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-, sulfate Octatensin (2-(Octahydro-1-azocinyl)ethyl)guanidine sulfate Sanoten Oktadin NSC 29863 beta-1-Azacyclooctylethylguanidine sulfate Guanetidin sulfate Octadine Guanetidin Sulfate Octadin Azocine, 1-(2-guanidinoethyl)octahydro-, sulfate (2:1) N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine Sulfate Guanethidine sulfate NSC-29863 Guanethidine bisulfate |
| Chemical Name Translation | 硫酸胍 |
| Wiswesser Line Notation | T8NTJ A2MYZUM & 2WSQQ |
| PubChem Substance ID | 65328 |
| InChI | InChI=1S/2C10H22N4.H2O4S/c2*11-10(12)13-6-9-14-7-4-2-1-3-5-8-14;1-5(2,3)4/h2*1-9H2,(H4,11,12,13);(H2,1,2,3,4) |
| MDL Number |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Amines
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Antihypertensive; antiglaucoma
相关文献及参考
- Al-Shora, H., et al.: Int. J. Pharm., 47, 209 (1988),
- Golander, Y., et al.: J. Pharm. Sci., 77, 902 (1988),
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,22,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 112 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : URXXAF U.S.S.R. Patent Document. (Gosudarstvennyi Komitet SSSR po Delam Izobretenii i Otkrytii, Malyi Tcherkasski pereulok 2/6, Moscow, Russia). Volume(issue)/page/year: #0822829
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 23 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 128,22,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#08547
TYPE OF TEST : LD50 - Letha
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - man DOSE : 391 mg/kg SEX/DURATION : male 78 week(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - other effects on male Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) REFERENCE : JSXRAJ Journal of Sex Research. (Soc. for the Scientific Study of Sex, Inc., Mt. Royal & Guilford Aves., Baltimore, MD 21202) V.1- 1965- Volume(issue)/page/year: 3,69,1967
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rat DOSE : 1400 mg/kg SEX/DURATION : male 56 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - other effects on male Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) REFERENCE : BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 48,30,1973
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - rat
DOSE : 900 mg/kg
SEX/DURATION : female 14 day(s) pre-mating
female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 56,715,1979
京ICP备2020036287号