4-(Phenylazo)aniline 4-氨基偶氮苯

CAS 60-09-3 MFCD00007854

化学结构图

60-09-3
SMILES: Nc1ccc(N=Nc2ccccc2)cc1

化学属性

Mol. FormulaC12H11N3
Mol. Weight197.24
Boiling Point>360
Melting Point123.0 to 127.0 deg-C
Solubility微溶于热水,溶于热醇、醚、苯、氯仿。
Density1.12
Stability对光敏感

别名和识别编码

Chemical Name4-(Phenylazo)aniline
CAS Number60-09-3
Alfabeta NamePHENYLDIAZENYLANILINE E42[]()---
MDL NumberMFCD00007854
Synonym 4-Aminoazobenzene {LY} 4-Aminoazobenzene {} {LY} 4-Aminoazobenzene {} {} {LY} 4-Aminoazobenzene {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoazobenzene {} {} {} {} {} {} {} {} {}
PubChem Substance ID87574394
EC Number200-453-6
Beilstein Registry Number16(1)310
Reaxys-RN743999
Merck Number419
Chemical Name Translation4-氨基偶氮苯
Wiswesser Line NotationZR DNUNR
InChIInChI=1S/C12H11N3/c13-10-6-8-12(9-7-10)15-14-11-4-2-1-3-5-11/h1-9H,13H2
Canonical SMILESNC1=CC=C(/N=N/C2=CC=CC=C2)C=C1
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分类

  • {SNA} 2002/61/E
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Hematology and Histology, P, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} 2002/61/EC, A, A-B, AM to AQ, All alphabetical sorted, Alpha Sort, Alphabetical Index of Analytical Standards, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Aryl Amines MAK III, Category 2, Chemical Class, Chromatography, Colors, Environmental Standards, European Community: ISO, DIN and DL 152, Method and Regulation Specific, Oeko-Tex Standard 100, Volatiles/ Semivolatiles
  • {SNA} 2002/61/EC,

产品应用

  • 酸碱指示剂及检验亚硝酸盐。有机合成。

相关文献及参考

  • Jack T. Spadaro, Michael H. Gold, Degradation of Azo Dyes by the Lignin-Degrading Fungus Phanerochaete chrysosporium Appl. Environ. Microbiol. 58(8) , 2397-2401, (1992)
  • Merck 14 ,419
  • Beil. 16 ,IV,445
  • Aldrich MSDS 1 , 1456:B / Corp MSDS 1 (2), 2762:C / FT-IR 1 (2), 969:D / FT-IR 2 (3), 4074:C / IR-Spectra (2), 1263:B / IR-Spectra (3), 1452:E / NMR-Reference 2 (2), 979:D / RegBook 1 (2), 2737:F / Sax 6 , 2174 / Sigma FT-IR 1 (2), 195:B / Stains and Dyes Ref , 568 / Structure Index 1 , 432:A:6
  • Short: II/27B Title: Diamagnetic Susceptibility of Organic Compounds, Oils, Paraffins and Polyethylenes Author: Kumar, M.; Gupta, R. Editor: Gupta, Radha Raman Source: Landolt-Börnstein, New Series Volume: II/27B Year: 2008 Keyword: diamagnetic susceptibility; organic compounds ISBN: 978-3-540-44359-9 (print) ISBN: 978-3-540-45860-9 (online) Internet Resource: doi:10.1007/978-3-540-45860-9 RefComment: VIII, 503 p. With CD-ROM., Hardcover RefComment: Written for: Scientists and researchers in the fields of physics, chemistry, materials science RefComment: Supplement and Revised Editon to II/16 Abstract: The volume II/27 has been divided into three subvolumes according to the classes of compounds: Subvolume A: Diamagnetic susceptibility and magnetic anisotropy of inorganic and organometallic compounds; Subvolume B: Diamagnetic susceptibility of organic compounds, oils, paraffins and polyethylenes; Subvolume C: Diamagnetic susceptibility and magnetic anisotropy of organic compounds. The data presented in this volume are based on the literature survey of the chemical abstracts up to 2005. The calculated values of diamagnetic susceptibility of organic compounds in the present subvolume II/27B are presented along with their experimental values. They have been calculated with the use of structural parameters in structural formula by using different theor

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H350 May cause cancer 可能致癌
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type N95 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T,N T,N,Xi
RTECSBY8225000
Precautionary statements
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P308+P311
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P302+P352+P333+P313+P362+P364
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P308+P313
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P405 Store locked up. 上锁保管。
  • P301+P312+P330
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P302+P350
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
Signal word
UN Number UN 3077 9/PG 3 3077
Safety Statements
Risk Statements
  • R45 May cause cancer 可能致癌
  • R50/53
Packing GroupIII
Hazard Class9
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   44,2540,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1965 mg/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 1

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 89 gm/kg/57W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intrarenal
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   24,1969,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent -

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 389,3,1997

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 10600 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 97,49,1982

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1 umol/L
REFERENCE :
   AMOKAG Acta Medicia Okayama.  (Okayama Univ. Medical School, Okayama, Japan)
    V.27    1973-  Volume(issue)/page/year: 30,303,1976

{haz

{hazard_com

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 700 ug/well
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 46,53,1977

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 5 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,11,1981

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse Bacteria - Salmonella typhimurium
DOSE/DURATION           : 125 mg/kg
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 62,911,1979

TYPE OF TEST

其他信息

  • 用途三:酸碱指示剂及检验亚硝酸盐。有机合成。
  • 方法一:以苯胺出发,重氮化后再与苯胺缩合经转位重排而得。向反应锅投入苯胺与亚硝酸钠溶液,在30-40℃下搅拌,在2.5-3h内加入30%盐酸,然后升温至50-55℃进行转位。
  • 色指数:11000
  • 4-阿基苯甲酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P0141 4-氨基偶氮苯 4-Aminoazobenzene 500G 3760元 2014/06/02 P0141 4-氨基偶氮苯 4-Aminoazobenzene 25G 416元
  • TCI Shanghai:4-氨基偶氮苯 4-Aminoazobenzene,>;95.0%(T)(60-09-3)
  • 用途一:用于制偶氮染料和恶嗪染料等,并用作醇溶黄和pH值指示剂
  • 易溶于乙醇、苯、三氯甲烷等,微溶于水。最大吸收波长386nm。半数致死量(小鼠,腹腔)200mg/kg。曾有实验动物致癌试验阳性报道。
  • MSDS 信息:氨基偶氮苯(60-09-3).msds
  • MOL 文件:60-09-3.mol
  • Sigma Aldrich:60-09-3(sigmaaldrich)
  • 下游产品:分散黄RGFL --> 酸性媒介橙6 --> 酸性红 73 --> 直接耐晒橙GGL --> 光致变色偶氮苯聚合物 --> 直接绿B
  • 外观性质:黄色结晶。
  • 图谱信息:4-阿基苯甲酯(60-09-3)核磁图( 1 HNMR) 4-阿基苯甲酯(60-09-3)红外图谱(IR1) 4-阿基苯甲酯(60-09-3)核磁图( 13 CNMR) 4-阿基苯甲酯(60-09-3)质谱(MS) 4-阿基苯甲酯(60-09-3)红外图谱(IR2)
  • 用途二:染料中间体。用于合成偶氮染料,分散染料、噁嗪染料;还用于制油漆和颜料,以及醇溶黄和pH指示剂。

系列性分类


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