Mecamylamine [INN:BAN]

CAS 60-40-2 MFCD00242582

化学结构图

60-40-2
SMILES: CNC1(C)C2CCC(C2)C1(C)C

化学属性

Mol. FormulaC11H21N
Mol. Weight167.33
Refractive index1.4875
Flash Point58 ºC
Melting Point245-256 ºC
Boiling Point189 ºC
Density0.91

别名和识别编码

Chemical NameMecamylamine [INN:BAN]
EC Number200-476-1
Synonym Mecamylamine Mecamine Inversine 3-Methylaminoisocamphane Mecamilamina Versamine Mekamine 2-Methylamino-2,3,3-trimethylnorborane 2-Methylaminoisocamphane 2-Methylamino-2,3,3-trimethylnorbornane N,2,3,3-Tetramethyl-2-norbornamine Mecamine; Revertina; N-Methyl-2-isocamphanamine; N,2,3,3-Tetramethyl-2-norcamphanamine; 2-(Methylamino)-2,3,3-trimethylnorbornane 3-Methylaminoisokamfan N,2,3,3-Tetramethyl-2-norcamphanamine 3-beta-Methylamino-2,2,3-trimethylbicyclo(2.2.1)heptane N-Methyl-2-isocamphanamine Mevasine Revertina
CAS Number60-40-2
Wiswesser Line NotationL55 ATJ CM1 C1 D1 D1
PubChem Substance ID4032
InChIInChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3
InChIKeyIMYZQPCYWPFTAG-UHFFFAOYSA-N
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安全信息

RTECSRB6880000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 25,163,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,490,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   10,905,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4168308

系列性分类

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