Quinuclidin-3-Yl Acetate Hydrochloride 奎宁环-3-基乙酸酯盐酸盐

CAS 6109-70-2 MFCD00136230

化学结构图

6109-70-2
SMILES: CC(=O)OC1CN2CCC1CC2.Cl

化学属性

Mol. FormulaC9H16ClNO2
Mol. Weight205.68
Boiling Point221.5°C at 760 mmHg
Flash Point85°C
Melting Point166 °C

别名和识别编码

Chemical NameQuinuclidin-3-Yl Acetate Hydrochloride
CAS Number6109-70-2
Synonym Aceclidine (hydrochloride) {LY} Aceclidine (hydrochloride) {} {LY} Aceclidine (hydrochloride) {} {} {LY} Aceclidine (hydrochloride) {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Aceclidine (hydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00136230
Chemical Name Translation奎宁环-3-基乙酸酯盐酸盐
EC Number228-071-5
Wiswesser Line NotationT66 A B CNTJ AOV1 &GH
LabNetwork Molecule IDLN01343822
Canonical SMILESCC(OC1C[N@@]2CC[C@H]1CC2)=O.Cl
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分类

  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Aceclidine is a synthetic analogue of Arecoline, a natural cholinomimetic alkaloid. Aceclidine acts as an agonist at cholinergic receptors and has therapeutic use to reduce intraocular pressure in gla

相关文献及参考

  • Hubbard, W. C., et al.: Ophthalmol., 210, 303 (1996),
  • Romano, J.H., et al.: Br. J. Ophthalmol., 54, 510 (1970),

安全信息

Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed
RTECSVD6198000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 165 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 23,398,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 23,398,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,322,1968

TYPE OF TEST            : LD50 -

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,322,1968

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系列性分类

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