4-Hydroxy-3,5-Diiodobenzoic Acid 4-羟基-3,5-二碘苯甲酸

CAS 618-76-8 MFCD00016532

化学结构图

618-76-8
SMILES: O=C(O)c1cc(I)c(O)c(I)c1

化学属性

Mol. FormulaC7H4I2O3
Mol. Weight389.92
Melting Point275°C
TSCAYes
Boiling Point346.4±42.0 °C at 760 mmHg

别名和识别编码

Chemical Name4-Hydroxy-3,5-Diiodobenzoic Acid
CAS Number618-76-8
Synonym 4-Hydroxy-3,5-diiodobenzoic acid {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-diiodobenzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Hydroxy-3,5-
MDL NumberMFCD00016532
EC Number210-562-0
Beilstein Registry Number2212145
Chemical Name Translation4-羟基-3,5-二碘苯甲酸
Wiswesser Line NotationQVR DQ CI EI
LabNetwork Molecule IDLN00216302
PubChem Substance ID12065
InChIInChI=1S/C7H4I2O3/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,10H,(H,11,12)
Canonical SMILESO=C(O)C1=CC(I)=C(O)C(I)=C1
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Used in the preparation of Thyroid hormone analogues.

安全信息

RTECSDG8597500
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C {LY} 2-8°C Light Sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 43,495,1954

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,20,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOCEAH Journal of Organic Chemistry.  (American Chemical Soc., Distribution
   Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037)  V.1-
   1936-  Volume(issue)/page/year: 22,1686,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,213,1960

Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • Alfa Aesar:3,5-二碘-4-羟基苯甲酸,97% 3,5-Diiodo-4-hydroxybenzoic acid, 97%(618-76-8)
  • MOL 文件:618-76-8.mol
  • 4-羟基-3,5-二碘苯甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/05/25 L02595 3,5-二碘-4-羟基苯甲酸, 97% 3,5-Diiodo-4-hydroxybenzoic acid, 97% 50g 2842元 2010/05/25 L02595 3,5-二碘-4-羟基苯甲酸, 97% 3,5-Diiodo-4-hydroxybenzoic acid, 97% 10g 738元
  • 敏感性:Light Sensitive

系列性分类


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