Benzamidine, 4,4'-(trimethylenedioxy)di-, dihydrochloride

CAS 6275-69-0 MFCD06275690

化学结构图

6275-69-0
SMILES: Cl.Cl.N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2)cc1

化学属性

Mol. Weight385.33
Mol. FormulaC17H20N4O2.2ClH

别名和识别编码

Wiswesser Line NotationMUYZR DO3OR DYZUM &GH 2
Chemical NamePanamidin dihydrochloride
Synonym 1,3-bis(p-amidinophenoxy)propane 1,3-di-(4-amidinophenoxy)propane 1,3-di-(p-amidinophenoxymethyl)-propane 4,4'-(trimethylenedioxy)dibenzamidine Benzenecarboximidamide, 4,4'-(1,3-propanediylbis(oxy))bis-, DAPP-Br DAPP-H propamidine propamidine dihydrochloride
CAS Number6275-69-0
InChIKeyUCMKQLSOWSNOED-UHFFFAOYSA-N
PubChem Substance ID80467
InChIInChI=1S/C17H20N4O2.2ClH/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21;;/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21);2*1H
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安全信息

RTECSCV6580000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Lungs, Thorax, or Respiration - other changes
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   ATMPA2 Annals of Tropical Medicine and Parasitology.  (Grune & Stratton,
   Inc., POB 6280, Duluth, MN 55806)  V.1-    1907-  Volume(issue)/page/year:
   37,1,1943

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35100 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 2,581,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ANTCAO Antibiotics and Chemotherapy (Washington, DC).  (Washington, DC)
   V.1-12, 1951-62.  For publisher information, see CLMEA3.
   Volume(issue)/page/year: 2,581,1952

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