Lactose 乳糖

CAS 63-42-3 MFCD00064521

化学结构图

63-42-3
SMILES: O=C[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)CO

化学属性

Mol. FormulaC12H22O11
Mol. Weight342
Melting Point224°C
TSCAYes
Density1.768

别名和识别编码

Chemical NameLactose
MDL NumberMFCD00064521
CAS Number63-42-3
Synonym Lactin B-4-(B-D-GALACTOSIDO)-D-GLUCOSE D-LACTOSE 4-O-Hexopyranosylhexopyranose 4-o-beta-d-galactopyranosyl-beta-d-glucopyranos ~-D-乳糖 ~-D-Lactose,contains80%~and20%alpha β-Lactose β-D-Gal-(1→4)-β-D-Glc B-LACTOSE MOLECULAR BIOLOGY GRADE D-Glucose, 4-O-beta-D-galactopyranosyl- Β-D-乳糖, CONTAINS ^=80% ^B AND ^=20% ^A β-D-Gal-(1→4)-β-D-Glc Saccharum lactin BETA-D-LACTOSE GAL1-B-4GLC B-LACTOSE D-Lactose B-LACTIN BETA-D-LACTOSE CA 80% BETA AND 20% ALPHA 4-(beta-D-Galactosido)-D-glucose B-LACTOBIOSE 4-O-BETA-D-GALACTOPYRANOSYL-BETA-D-GLUCOPYRANOSE BETA-D-GAL-[1->4]-BETA-D-GLC B-MILK SUGAR D-(+)-LACTOSE Lactobiose Milk sugar β-D-Gal-(1→4)-β-D-Glc β-Lactose β-乳糖 .beta.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl- Lactose, beta- BETA-LACTOSE
EC Number200-559-2
PubChem Substance ID24896352
Merck Number14,5343
Chemical Name Translation乳糖
InChIKeyGUBGYTABKSRVRQ-DCSYEGIMSA-N
Wiswesser Line NotationT6OTJ BQ CQ DQ F1Q EO- BT6OTJ CQ DQ EQ F1Q -D
Beilstein Registry Number0093796
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分类

  • {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates H-L, Disaccharide
  • {SNA} Carbohydrates A to Z, Carbohydrates H-L, Disaccharide, 生化试剂, 碳水化合物

产品应用

  • 细胞培养基组分。

相关文献及参考

  • Merck:14,5343
  • [1]. Kleessen B, et al. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr. 1997 May;65(5):1397-402.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSOD9625000
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1000 gm/kg/29w-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   46,363,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,2427,1975

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 375 mg/kg
SEX/DURATION            : female 4-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 4,497,1971

其他信息

  • β-乳糖价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 63008181 β-乳糖 10g 124元 2010/06/21 412980020 β-乳糖 beta-D-Lactose , ca 80% beta and 20% alpha 2 KG 1775元 2010/06/21 412985000 β-乳糖 beta-D-Lactose , ca 80% beta and 20% alpha 500 GR 594元
  • Sigma Aldrich:5965-66-2(sigmaaldrich)
  • 乳糖特性： 由哺乳动物的乳中分出的一种双糖。牛乳中约含4%-5%，人乳中约含6.7%。经酸性水解得等分子的D-葡萄糖和D-半乳糖。是还原糖，能还原费林溶液。在常温水溶液中结晶得α-乳糖，在93℃以上结晶得β-乳糖。α-乳糖即普通的乳糖。有微弱的甜味，快速加热，其水溶液有变旋现象，[a]20D-92.6°→+83.5°(10分钟）→+69°(50分钟)→+52.3°(22小时)。β-乳糖比α-乳糖稍甜。其水溶液也有变旋现象。[α]25D+34°(3分钟)→+39°(6分钟)→+46°(1小时)→52.3°
  • 用途一:细胞培养基组分。
  • 外观性质:乳糖特性：由哺乳动物的乳中分出的一种双糖。牛乳中约含4%-5%，人乳中约含6.7%。经酸性水解得等分子的D-葡萄糖和D-半乳糖。是还原糖，能还原费林溶液。在常温水溶液中结晶得α-乳糖，在93℃以上结晶得β-乳糖。α-乳糖即普通的乳糖。有微弱的甜味，通常带一分子结晶水。呈单斜晶体。120℃时失去结晶水，快速加热，熔点201-202℃。其水溶液有变旋现象，[a]20D-92.6°→+83.5°(10分钟）→+69°(50分钟)→+52.3°(22小时)。β-乳糖比α-乳糖稍甜。白色晶体。熔点252℃。其水溶液也有变旋现象。[α]25D+34°(3分钟)→+39°(6分钟)→+46°(1小时)→52.3°(22小时)。β-乳糖在常温吸水后能转变成α-乳糖，后者加热至93℃以上又变成β-乳糖。乳糖溶于水，微溶于甲醇、乙醇，不溶于乙醚和氯仿。β-乳糖特性：溶于水，微溶于乙醇，不溶于乙醚、氯仿熔点:224 °Calpha:55.15° (c=10, H2O/NH3)
  • Acros Organics:bata-D-乳糖 beta-D-Lactose, ca 80% beta and 20% alpha(5965-66-2)
  • Alfa Aesar:β-D-乳糖,contains^=80%^band^=20%^a beta-D-Lactose, contains ≈80% beta and ≈20% alpha(5965-66-2)
  • MOL 文件:5965-66-2.mol

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Disaccharide - Carbohydrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Disaccharide - Carbohydrates
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. Microbial Media for Molecular Biology - Molecular Biology
  4. Media Components - Microbial Media for Molecular Biology
  5. Media Reagents - Media Components
  1. Functional Group 官能团索引
  2. hemiacetal
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Carbohydrates
  4. Agarose
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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