2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-allyl-6-ethyl-11-methyl-

CAS 6654-31-5 MFCD N/A

化学结构图

6654-31-5
SMILES: C=CCN1CCC2(CC)c3cc(O)ccc3CC1C2C

化学属性

Mol. FormulaC18H25NO
Mol. Weight271.44

别名和识别编码

Chemical Name2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-allyl-6-ethyl-11-methyl-
Chemicalbook IDCB82325246
Synonym 2-Allyl-5-ethyl-2'-hydroxy-9-methyl-6,7-benzomorphan 2,6-Methano-3-benzazocin-8-ol,
CAS Number6654-31-5
Wiswesser Line NotationT C666 A KN&TTJ A1 B2 EQ K2U1
Beilstein Registry Number1384926
InChIKeyDVLZNYFUUUDCOL-UHFFFAOYSA-N
PubChem Substance ID110913
InChIInChI=1S/C18H25NO/c1-4-9-19-10-8-18(5-2)13(3)17(19)11-14-6-7-15(20)12-16(14)18/h4,6-7,12-13,17,20H,1,5,8-11H2,2-3H3
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安全信息

RTECSPB8500000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human
DOSE/DURATION           : 70 ug/kg
TOXIC EFFECTS :
   Behavioral - toxic psychosis
   Behavioral - antipsychotic
   Gastrointestinal - nausea or vomiting
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   137,541,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 174 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 143,141,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 182 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 143,141,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   31ZPAG "Synthetic Analgesics," Oxford, Pergamon Press, 1966
   Volume(issue)/page/year: 2,175,1966

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