4-aminoisoxazolidin-3-one dl-环丝氨酸
CAS 68-39-3 MFCD00064323
化学结构图
SMILES: NC1CONC1=O
化学属性
| Mol. Formula | C3H6N2O2 |
|---|---|
| Mol. Weight | 102.09 |
| Melting Point | 138-141°C |
别名和识别编码
| Chemical Name | 4-aminoisoxazolidin-3-one |
|---|---|
| CAS Number | 68-39-3 |
| Synonym | DL-Cycloserine {LY} DL-Cycloserine {} {LY} DL-Cycloserine {} {} {LY} DL-Cycloserine {} {} {} {LY} DL-Cycloserine {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} DL-Cycloserine {} {} {} {} {} {} {} {} {} |
| MDL Number | MFCD00064323 |
| PubChem Substance ID | 24278332 |
| EC Number | 200-687-9 |
| Chemical Name Translation | dl-环丝氨酸 |
| Wiswesser Line Notation | T5OMVTJ DZ -+- |
| InChIKey | DYDCUQKUCUHJBH-UHFFFAOYSA-N |
| LabNetwork Molecule ID | LN00219721 |
| Canonical SMILES | NC1CONC1=O |
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分类
- {S
- {SNA} A to C, Alanine hydroxymethyltransferase, D-, Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
- Heterocycles
- Pharmaceuticals
- {SNA} A to C, Alanine hydroxymethyltransferase, D-, Bioactive Small Molecules, Biochemicals and Reagents, CI-CY, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Peptides and Proteins, Peptides for Cell Biology, 细胞生物学
- {SNA} A to C, Alanine hydroxymethyltransferase, D-, Bioactive Small Molecules,
产品应用
- An alanine aminotransferase and ketosphinganine synthetase inhibitor.
相关文献及参考
- Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972),
- 1. Huang, J., et al., The glutathione dependence of inorganic sulfate formation from L- or D-cysteine in isolated rat hepatocytes Chem. Biol. Interact. 110 , 189-202, (1998) 摘要
- Edmondson, J. Biochem. Biophys. Res. Commun. 76 , 751, (1977)
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,298,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2814 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,447,1958
其他信息
- rac Cycloserine is an alanine aminotransferase and ketosphinganine synthetase inhibitor. It is also an inhibitor of other pyridoxal-phosphate-requiring transaminases.
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