Imidazo(4,5-c)thieno(1,2-a)thiolium,1,3-dibenzyldecahydro-2-oxo-,2-oxo-10-boranesulfonate

CAS 68-91-7 MFCD01720171

化学结构图

68-91-7
SMILES: CC1(C)[C@@H]2CC(=O)[C@@]1(CS(O)(=O)=O)CC2.O=C1N(CC2C=CC=CC=2)C2C(C[S+]3CCCC32)N1CC1C=CC=CC=1 |&1:3,7|

化学属性

Mol. FormulaC22H25N2OS.C10H15O4S
Mol. Weight596.86

别名和识别编码

Chemical NameImidazo(4,5-c)thieno(1,2-a)thiolium,1,3-dibenzyldecahydro-2-oxo-,2-oxo-10-boranesulfonate
Wiswesser Line NotationVTJ A A &13/29
Synonym Camfosulfonato del Arfonad camphorsulfonate Arfonad roche Arfonad Arphonad
CAS Number68-91-7
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安全信息

RTECSNJ6100000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 141 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 28,495,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2024 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - nausea or vomiting
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 19,727,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 141 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - nausea or vomiting
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 19,727,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Blood - hemorrhage
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/y

系列性分类

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