Cyclopenthiazide 环戊噻嗪
CAS 742-20-1 MFCD00865825
化学结构图
SMILES: NS(=O)(=O)c1cc2c(cc1Cl)NC(CC1CCCC1)NS2(=O)=O
化学属性
| Mol. Formula | C₁₃H₁₈ClN₃O₄S₂ |
|---|---|
| Mol. Weight | 379.88 |
| Appearance | 白色粉末。熔点238-242℃，溶于乙醇、乙醚、丙酮，微溶于氯仿，不溶于水，无臭，几乎无味。 |
| Melting Point | 229 - 234°C |
| Boiling Point | |
| Flash Point | - |
别名和识别编码
| Chemical Name | Cyclopenthiazide |
|---|---|
| CAS Number | 742-20-1 |
| Synonym | ######## 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide (6CI, 8CI, 9CI) 2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dih 3-Cyclopentylmethyl hydrochlorothiazide deriv 3-cyclopentylmethylhydrochlorothiazidederiv 3-环戊甲基-6-氯-3,4-二氢-2H-1,2,4-苯并噻二嗪-7-磺酰胺 1,1-二氧化物 6-Chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-7-sulfamyl-2H-1,2,4-benzothiadiazine 1,1-dioxide 6-Chloro-3-[cyclopentylmethyl]-3,4-dihydro-[2H]-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide 6-Chloro-3-cyclopentylmethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide 6-chloro-3- |
| EC Number | 212-012-5 |
| MDL Number | - |
| Chemical Name Translation | 环戊噻嗪 |
| Wiswesser Line Notation | T66 BSWM EM DHJ HG ISZW D1- AL5TJ |
| Beilstein Registry Number | 0630346 |
| PubChem Substance ID | 2904 |
| InChI | InChI=1S/C13H18ClN3O4S2/c14-9-6-10-12(7-11(9)22(15,18)19)23(20,21)17-13(16-10)5-8-3-1-2-4-8/h6-8,13,16-17H,1-5H2,(H2,15,18,19) |
| Canonical SMILES | - |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
- Cyclopenthiazide is a thiazide diuretic. Cyclopenthiazide is used in the treatment of oedema caused by conditions such as kidney disease, liver cirrhosis and pre-menstrual syndrome as well as in the t
相关文献及参考
- Davila, D. et al.: Acta Biol. Med. Exp., 5, 1(1980); Frenzel, J. et al.: Acta Paed. Acad. Sci. Hing., 15, 157 (1974); Takamura, N. et al.: Pharmac. Res., 11, 1452 (1994);
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 142 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 131,325,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,314,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 232 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 131,325,1961
其他信息
- 用途一:用于治疗水肿及高血压症。
- MOL 文件:742-20-1.mol
- 方法一:环戊基乙醛与4,6-二磺酰胺-3-氯苯胺环合而得。
京ICP备2020036287号