Urea, N-hydroxy-N-methyl- (9CI) 1-羟基-1-甲基脲

CAS 7433-43-4 MFCD N/A

化学结构图

7433-43-4
SMILES: CN(O)C(N)=O

化学属性

Mol. Weight90.08
Mol. FormulaC2H6N2O2
Melting Point65-68 °C

别名和识别编码

CAS Number7433-43-4
Chemical NameUrea, N-hydroxy-N-methyl- (9CI)
Synonym 1-Hydroxy-1-methylurea {LY} 1-Hydroxy-1-methylurea {} {LY} 1-Hydroxy-1-methylurea {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-1-methylurea {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Hydroxy-
Chemical Name Translation1-羟基-1-甲基脲
Beilstein Registry Number1921679
InChIKeyOCWOEDAIWSVHFT-UHFFFAOYSA-N
PubChem Substance ID81934
InChIInChI=1S/C2H6N2O2/c1-4(6)2(3)5/h6H,1H3,(H2,3,5)
Canonical SMILESO=C(N)N(O)C
MDL NumberMFCD01675994
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • 1-Methylhydroxyurea is a methylated hydroxyurea with anticancer activity. 1-Methylhydroxyurea has been shown to inhibit the growth of tumors by impairing DNA replication, without interfering with cont

相关文献及参考

  • Hilf, R. et al.: Cancer Res., 26, 2286 (1966); Gale, G.R. et al.: Biochem. Pharmacol., 17, 235 (1968); Yu, R.J. et al.: J. INvest. Dermatol., 63, 279 (1974);

安全信息

RTECSYT4971000 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intravaginal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1 pph
REFERENCE :
   JIDEAE Journal of Investigative Dermatology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.1-    1938- Volume(issue)/page/year:
   63,279,1974

Storage condition

系列性分类

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