Hydroxychloroquine Sulfate 硫酸羟基氯喹

CAS 747-36-4 MFCD00078203

化学结构图

747-36-4
SMILES: CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12.O=S(=O)(O)O

化学属性

Mol. FormulaC18H26ClN3O·H2SO4
Mol. Weight434
Melting Point240 ºC
Solubility易溶

别名和识别编码

Chemical NameHydroxychloroquine sulfate, 98%
CAS Number747-36-4
Alfabeta NameCHLOROQUINOLINYLAMINOPENTYLETHYLAMINOETHANOLSULFATE 2474((((()))))------
MDL NumberMFCD00078203
Synonym Hydroxychlorochin Hydroxychloroquine Hydroxychloroquine Sulfate Hydroxychloroquine Sulfate (1:1) Salt Oxychlorochin Oxychloroquine Plaquenil {} {} {} 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
EC Number212-019-3
Reaxys-RN7242072
PubChem Substance ID12947
Merck Number4818
Chemical Name Translation硫酸羟基氯喹
LabNetwork Molecule IDLN00176750
InChIInChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
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分类

  • {SNA} Analytical Standards, Chromatography, Pharmaceutical Standards, Pharmacopeia Standards, USP Standards, USP Standards G - H, 分析/色谱
  • {SNA} Analytical Standards, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards G - H, 分析/色谱
  • {SNA} Antioxidants and Cytoprotectants, Bioactive Small Molecule Alphabetical Index, Cell Stress, H, Nitric Oxide and Cell Stress, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Antioxidants and Cytoprotectants, Cell Signaling and Neuroscience, Cell Stress, Nitric Oxide and Cell Stress, 细胞生物学
  • Heterocycles
  • {SNA} Analytical Standards, Analytical/Chromatograp
  • {SNA} B

产品应用

  • An antimalarial; antirheumatic; lupus erythematosus suppressant.

相关文献及参考

  • Yarden, Y., et al.: Nature, 323, 226 (1986),

安全信息

Warnings IRRITANT
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P317
  • P333+P313
  • P333+P317
  • P337+P313
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
RTECSKK3342500
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn Xn,Xi Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Cardiac - other changes
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   JATOD3 Journal of Analytical Toxicology.  (Preston Pub. Inc., POB 48312,
   Niles, IL 60648) V.1-    1977-  Volume(issue)/page/year: 14,186,1990

其他信息

  • RTECS号:KK3342500
  • MOL 文件:747-36-4.mol
  • 硫酸羟基氯喹价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H1306 硫酸羟基氯喹 Hydroxychloroquine Sulfate 5G 558元 2014/06/02 H1306 硫酸羟基氯喹 Hydroxychloroquine Sulfate 25G 1890元 2010/06/21 263011000 硫酸羟基氯喹 Hydroxychloroquine sulfate 98% 100 GR 5004元

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Nitric Oxide and Cell Stress - Cell Signaling and Neuroscience
  5. Cell Stress - Nitric Oxide and Cell Stress
  6. Antioxidants and Cytoprotectants - Cell Stress
  1. Functional Group 官能团索引
  2. sulfuric acid
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. New Products
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Nitric Oxide and Cell Stress
  5. Cell Stress

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