N-Methyl-N-formylhydrazine N-甲基甲酰肼

CAS 758-17-8 MFCD00758178

化学结构图

758-17-8
SMILES: CN(N)C=O

化学属性

Mol. Weight74.08
Mol. FormulaC2H6N2O
Melting Point219-222 °C
Boiling Point131.34 °C at 760 mmHg

别名和识别编码

Chemical NameN-Methylformohydrazide
Synonym N-Methylformohydrazide {LY} N-Methylformohydrazide N-methyl-N-formylhydrazine {} {LY} N-Methylformohydrazide {} {} {LY} N-Methylformohydrazide {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformohydrazide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylformoh
Beilstein Registry Number2036827
CAS Number758-17-8
Chemicalbook IDCB31309581
Chemical Name TranslationN-甲基甲酰肼
PubChem Substance ID12962
InChIInChI=1S/C2H6N2O/c1-4(3)2-5/h2H,3H2,1H3
Canonical SMILESNN(C=O)C
MDL NumberMFCD01726298
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安全信息

TYPE OF TEST            : TDLo - Lowest publ

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 158 mg/kg/79W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   MYCPAH Mycopathologia.  (Kluwer Academic Pub. Group, Distribution Centre,
   POB 322, 3300 AH Dordrecht, Netherlands)  V.1-    1938-
   Volume(issue)/page/year: 78,11,1982

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 6,577,1980

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3920 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 27,25,1980

{h

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 187 mg/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   MYCPAH Mycopathologia.  (Kluwer Academic Pub. Group, Distri

RTECSLQ8940000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,363,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   45,429,1978

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 umol/plate
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 26,155,1983

Storage condition
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H351 Suspected of causing cancer 怀疑致癌
Precautionary statements
  • P203
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P316
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P316
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P317
  • P337+P317
  • P361+P364
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类


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