Dextran 葡聚糖

CAS 9004-54-0 MFCD00130935

化学结构图

9004-54-0
SMILES: CC[C@H]1OC(COC[C@H]2OC(COC)[C@@H](O)C(OC)C2O)[C@@H](O)C(O)C1O

化学属性

Mol. FormulaN/A
Mol. WeightMFCD00130935
Density1.047
Stability对湿度敏感
SolubilitySoluble in water (100 mg/ml), DMSO (freely), formamide (freely), ethylene glycol (freely), and glycerol (freely)

别名和识别编码

MDL NumberMFCD00130935
CAS Number9004-54-0
EC Number232-677-5
Synonym DEXTRAN 40 Dextran Dextran 40 Dextran 40000 Dextran 70 Dextran 75 Dextran 80 Dextran B 1355 Dextran B 1355 S Dextran B-1355 Dextran B-1355-S Dextran B1355 Dextran B512 Dextran Derivatives Dextran M 70 Dextran T 40 Dextran T 500 Dextran T 70 Dextran T-40 Dextran T-500 Dextrans Hemodex Hyskon Infukoll Low molecular dextran-L Macrodex Mucrose; Glucose polymer Polyglucin Promit Rheodextran Rheoisodex Rheomacrodex Rheopolyglucin Rondex Saviosol 右旋糖酐,葡聚精 右旋糖酐; 葡聚精 葡聚糖 来源于明串珠菌 属 葡聚糖 来源于肠系膜明串珠菌 葡聚糖 溶液 来源于肠系膜明串珠菌
Chemical NameDextran
Chemical Name Translation葡聚糖
Beilstein Registry Number232-677-5
PubChem Substance ID4125253
InChIInChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
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分类

  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Biochemicals and Reagents, Carbohydrates, Chromatography, D, DA - DH, Dextran, Dextran Standards for Gel Permeation Chromatography (GPC), Dextrans,
  • {SNA} Alphabetical Index of Analytical
  • {SNA} Analytical Standards, Analytical/Chromatogr

产品应用

  • 用于校准测定高分子材料分子量的仪器、评价测量方法和给高分子材料分子量特性量值赋值。

相关文献及参考

  • Merck: 14,2948

安全信息

WGK Germany2
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSHH9230000
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
Storage condition 储存温度2-8℃ 密封阴凉干燥保存。 储存温度 2-8°C ,充氩储存 储存温度2-8℃,充氩保存 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Endocrine - tumors
   Skin and Appendages - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST

TYPE OF

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 6,1023,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 6,1023,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 13500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GETRE8 Gematologiya i Transfuziologiya.  Hematology and Transfusion Science.
    (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.28-    1983-
   Volume(issue)/page/year: 31(10),38,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >12 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 6,1023,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraveno

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human - woman
DOSE                    : 2 mL/kg
SEX/DURATION            : female 38 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
   DRSAEA Drug Safety.  (Adis International Ltd.,  Private Bag 65901, Mairangi
   Bay, Auckland 10, New Zealand)  V.5-    1990-  Volume(issue)/page/year:
   7,71,1992

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 675 gm/kg
SEX/DURATION            : female 8-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 6,1119,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 3640 gm/kg
SEX/DURATION            : male 91 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 3,369,1975

其他信息

  • 易溶于水。微溶于乙醇，在中性溶液中很稳定，遇强酸及升高温度下被水解，在碱性溶液中端基能被氧化。无臭，无味。
  • Dextran a multi-use, branched glucan with long, hydrophilic spacer arms that improve the performance of immobilized proteins acting on macromolecules. Low molecular weight dextran is useful as a stabilizer, volume extender, lubricant, binding platform, and matrix component. Higher molecular weight dextrans have differing viscosities, aggregation and permeation properties.
  • Dextran a multi-use, branched glucan with long, hydrophilic spacer arms that improve the performance of immobilized proteins acting on macromolecules. Low molecular weight dextran is useful as a stabilizer, volume extender, lubricant, binding platform, and matrix component. Higher molecular weight dextrans have differing viscosities, aggregation and permeation properties
  • 固体

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Polysaccharide - Carbohydrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Dextrans - Carbohydrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Stabilization of Biomolecules - Biochemicals and Reagents
  4. Biostabilization Agents - Stabilization of Biomolecules
  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Density Gradient Media - Hematology and Histology
  4. Polysaccharides - Density Gradient Media
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. ACS - Analytical Reagents for General Use
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Reagents
  3. Analytical Reagents for General Use - Analytical Reagents
  4. Puriss p.a. - Analytical Reagents for General Use
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. D - Alphabetic
  5. DA - DH - D
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. D - Alphabetic
  5. DA - DH - D
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Polymer Standards - Chromatography
  5. Water Soluble Polymers - Polymer Standards
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Polymer Standards - Chromatography
  5. Polymer Standards Kits - Polymer Standards
  6. Water Soluble - Polymer Standards Kits
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Polymer Standards - Chromatography
  5. DIN Standards - Polymer Standards
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Carbohydrates - Biochemicals and Reagents
  4. Dextrans - Carbohydrates
  5. Dextran Standards for Gel Permeation Chromatography (GPC) - Dextrans
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Certified Reference Materials (CRMs) - Analytical Standards
  4. Application CRMs - Certified Reference Materials (CRMs)
  5. Polymer Standards - Application CRMs
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Carbohydrates
  4. Monosaccharide

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