Amiphenazole hydrochloride

CAS 942-31-4 MFCD00942314

化学结构图

942-31-4
SMILES: Cl.Nc1nc(N)c(-c2ccccc2)s1

化学属性

Mol. FormulaC9H9N3S.ClH
Mol. Weight227.73

别名和识别编码

Chemical NameAmiphenazole hydrochloride
Chemicalbook IDCB9908121
Wiswesser Line NotationT5N CSJ BZ DR& EZ &GH
Synonym Fenamizol hydrochloride Amiphenazole hydrochloride Amphenazole hydrochloride 5-Phenyl-2,4-thiazolediamine monohydrochloride Daptazole hydrochloride Amifenatsol hydrochloride 2,4-Thiazolediamine, 5-phenyl-, monohydrochloride Daftazol hydrochloride 2,4-Diamino-5-phenylthiazole hydrochloride 2,4-Diamino 5-phenylthiazol chlorhydrate Phenamizole hydrochloride Amphisol hydrochloride Daptazile hydrochloride 2,4-Diamino-5-phenylthiazole monohydrochloride Thiazole, 2,4-diamino-5-phenyl-, monohydrochloride
CAS Number942-31-4
InChIKeyAGSXNJJBDIOXIP-UHFFFAOYSA-N
PubChem Substance ID24276
InChIInChI=1S/C9H9N3S.ClH/c10-8-7(13-9(11)12-8)6-4-2-1-3-5-6;/h1-5H,10H2,(H2,11,12);1H
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安全信息

RTECSXJ4025000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 144 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 110,465,1957

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,489,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 159 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FRZKAP Farmatsevtichnii Zhurnal (Kiev).  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR) V.3-    1930-  Volume(issue)/page/year: 26(5),20,1971

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,201,1972

系列性分类

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