Phencyclidine hydrochloride 苯环利定

CAS 956-90-1 MFCD00058208

化学结构图

956-90-1
SMILES: Cl.c1ccc(C2(N3CCCCC3)CCCCC2)cc1

化学属性

Mol. FormulaC17H25N.ClH
Mol. Weight279.89

别名和识别编码

Chemical Name盐酸盐 Phencyclidine Hydrochloride
CAS Number956-90-1
Synonym GP 121 GP-121 Sernyl Phencyclidine hydrochloride Nsc-40902 1-(1-Phenylcyclohexyl)piperidine hydrochloride 1-(1-Phenylcyclohexyl)piperidine Hydrochloride DOA Sernylan Ci395 苯环利定 盐酸盐 Elephant tranquilizer Phencyclidine monohydrochloride 1-(1-Phenylcyclohexyl)piperidine hydrochloride PCP hydrochloride Piperidine, 1-(1-phenylcyclohexyl)-, hydrochloride HOG CI-395 NIH 9580 Cl 395 hydrochloride Peace pill Sernyl hydrochloride Phencyclidin Hydrochlorid CI395 CN-25,253-2 NSC-40902 C.I. 395 Elysion PCP hydrochloride Phenylcyclidine hydrochloride MCV 4158 Trank Angel dust
MDL NumberMFCD00058208
Wiswesser Line NotationT6NTJ A- AL6TJ AR &GH
Chemical Name Translation苯环利定
PubChem Substance ID9795678
InChIInChI=1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; alicycle; 6RingOnly; 6ring; 2fragments; ionic
  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids - Opiod Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neurobiology, Neuroscience, Opioid Agonists, Opioids, P, Pfizer Compounds, Pharmacologicals, Proteins and Derivatives

产品应用

  • Anesthetic (intravenous).

相关文献及参考

  • Chen, G., et al.: J. Pharmacol. Exp. Ther., 127, 241 (1959),
  • Bailey, K., et al.: J. Pharm. Pharmacol., 28, 713 (1976),
  • Balster, R.L., J. Psychedelic Drugs., 10115 (1978),
  • Short: III/10b Title: Structure Data of Organic Crystals: C 16 ... C 168 Author: Schudt-Weitz, G.; Strell, I. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: III/10b Year: 1985 ISBN: 3-540-13932-X ISBN: 978-3-540-13932-4 Internet Resource: DOI:10.1007/b19985 RefComment: XIX,652 pages. Hardcover

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P301+P310
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
RTECSTN2272600
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes T
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
Restrict 精神药品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 5600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 14 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   238,515,1977

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 77 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 28,713,1976

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 71 ug/kg
TOXIC EFFECTS :
   Behavioral - euphoria
   Behavioral - hallucinations, distorted perceptions
   Behavioral - excitement
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   238,515,1977

{ha

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 85 mg/kg
SEX/DURATION            : female 1-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - postpartum
REFERENCE :
   PSCHDL Psychopharmacology (Berlin).  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.47-    1976-
   Volume(issue)/page/year: 69,63,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 150 mg/kg
SEX/DURATION            : female 8-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   PBBHAU Pharmacology, Biochemistry and Behavior.  (ANKHO International Inc.,
   P.O. Box 426, Fayetteville, NY 13066)  V.1-    1973-
   Volume(issue)/page/year: 35,93,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 11 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
   DENED7 Developmental Neuroscience (Basel).  (S. Karger Pub., Inc., 79 Fifth
   Ave., New York, NY 10003) V.1-    1978-  Volume(issue)/page/year:
   12,204,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 50 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception

系列性分类


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