N-(4-Ethoxyphenyl)-4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)Thiazol-2-Amine N-(4-乙氧基苯基)-4-(2-甲基咪唑并[1,2-a]吡啶-3-基)噻唑-2-胺
CAS 315703-52-7 MFCD01044465
化学结构图
SMILES: CC1N=C2C=CC=CN2C=1C1=CSC(NC2=CC=C(C=C2)OCC)=N1
化学属性
| Mol. Formula | C19H18N4OS |
|---|---|
| Mol. Weight | 350.44 |
别名和识别编码
| Chemical Name | N-(4-Ethoxyphenyl)-4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)Thiazol-2-Amine |
|---|---|
| Synonym | N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine |
| CAS Number | 315703-52-7 |
| Chemical Name Translation | N-(4-乙氧基苯基)-4-(2-甲基咪唑并[1,2-a]吡啶-3-基)噻唑-2-胺 |
| PubChem Substance ID | 329815733 |
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分类
- Angiogenic Factors, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, Sonic Hedgehog
- {SNA} Angiogenic Factors, Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, J, Sonic Hedgehog,
相关文献及参考
- Cupido T, Rack PG, Firestone AJ, Hyman JM, Han K, Sinha S, Ocasio CA, Chen JK., The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling. Angew. Chem. Int. Ed. Engl. 13th ed., Stanford University 48 , 2321-2324, (2009) 摘要
- Lee J, Wu X, Pasca di Magliano M, Peters EC, Wang Y, Hong J, Hebrok M, Ding S, Cho CY, Schultz PG., A small-molecule antagonist of the hedgehog signaling pathway. ChemBioChem. 16th ed., The Scripps Research 8 , 1916-1919, (2007)
安全信息
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H318 Causes serious eye damage 严重伤害眼睛
- H302 Harmful if swallowed 吞食有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
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