Deacetyltaxol 7-表-10-去乙酰基紫杉醇

CAS 78432-77-6 MFCD01075779

化学结构图

78432-77-6
SMILES: CC1(C)C2[C@@H](O)C(=O)[C@@]3(C)[C@H]([C@H](OC(=O)C4C=CC=CC=4)[C@@]1(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)C1C=CC=CC=1)C1C=CC=CC=1)C=2C)[C@@]1(CO[C@@H]1C[C@@H]3O)OC(C)=O

化学属性

Mol. FormulaC45H49NO13
Mol. Weight811.87
Melting Point175-178

别名和识别编码

Chemical NameDeacetyltaxol
CAS Number78432-77-6
Synonym 10-Deacetyltaxol 10-Deacetylpaclitaxel
Chemical Name Translation7-表-10-去乙酰基紫杉醇
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • A semi-synthetic precursor of Paclitaxel.

相关文献及参考

  • [2]. Michel Colin, et al. Process for the preparation of taxol and 10-deacetyltaxol. US4857653A.
  • [3]. Helson L. Cephalomannine and 10-deacetyltaxol cytotoxicity in human glial and neuroblastoma cell-lines. Int J Oncol. 1993 Feb;2(2):297-9.
  • [1]. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9.
  • [1]. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9.
  • [2]. Michel Colin, et al. Process for the preparation of taxol and 10-deacetyltaxol. US4857653A.
  • [3]. Helson L. Cephalomannine and 10-deacetyltaxol cytotoxicity in human glial and neuroblastoma cell-lines. Int J Oncol. 1993 Feb;2(2):297-9.

安全信息

GHS Symbol
Safety Statements
Precautionary statements

系列性分类

  1. Medical Research Areas
  2. Cytosketetal Signaling
  3. Microtubule/Tubulin  (微管/微管蛋白)

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