Papaverine Hydrochloride 盐酸罂粟碱(精神类药品，不能销售)
CAS 61-25-6 MFCD00012745
化学结构图
SMILES:
化学属性
| Mol. Formula | C20H21NO4· HCl |
|---|---|
| Mol. Weight | 375.85 |
| Melting Point | ca 220° dec. |
| TSCA | Yes |
别名和识别编码
| Chemical Name | Papaverine Hydrochloride |
|---|---|
| CAS Number | 61-25-6 |
| Alfabeta Name | DIMETHOXYBENZYLDIMETHOXYISOQUINOLINEHYDROCHLORIDE 13467()----,, |
| MDL Number | MFCD00012745 |
| Synonym | Papaverine hydrochloride Papaverine monohydrochloride Papanerin-HCl Artegodan 6,7,3',4'-Tetramethoxy-1-benzylisoquinoline hydrochloride Pavakey Dynovas 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride 1-(3,4-二甲氧基苄基)-6,7-二甲氧基异喹啉盐酸盐, 99% Isoquinoline, 6,7-dimethoxy-1-veratryl-, hydrochloride Pavatest Therapav NCI-C56359 Dispamil Pavagrant Dipav Vasal 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline 6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride Pameion Spasmo-nit Pavased Chlorhydrate de papaverine Cardoverina Lapav Cerespan Optenyl Vasospan Cepaverin Pavabid Papavarine chlorhydrate |
| Beilstein Registry Number | 3921435 |
| EC Number | 200-502-1 |
| Merck Number | 14,7019 |
| PubChem Substance ID | 24278152 |
| Chemical Name Translation | 盐酸罂粟碱(精神类药品，不能销售) |
| InChIKey | XQYZDYMELSJDRZ-UHFFFAOYSA-N |
| Wiswesser Line Notation | T66 CNJ B1R CO1 DO1& HO1 IO1 &GH |
| LabNetwork Molecule ID | LN00156799 |
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分类
- {SNA} Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Chromatography, N - R, Papaver, Pharmaceutical Secondary Standards, Pharmaceutical Standards, Pharmacopeia & Metrological Institutes Standards, Phytochemical Standards, Phytochemical Standards by Plant Genus, Secondary Pharmaceutical Standards, 分析/色谱
- {SNA} Bioactive Small Molecule Alphabetical Index, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, P-PH, Phosphodiesterase Inhibitors, Therapy Adjuncts, 抗肿瘤药物, 生物活性小分子, 癌症研究, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Analytical Standards,
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S22 Do not breathe dust 不要吸入粉尘；
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 68800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,1109,1989
TYPE OF TEST : LD50 - Lethal do
TYPE OF TEST : TDLo - Lowest publi
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 14400 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,1109,1989
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 66 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4405627
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 123,264,1960
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Fibroblast DOSE/DURATION : 125 mg/L REFERENCE : ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (96),55,1978
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 340 mg/L REFERENCE : GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE : 140 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - Central Nervous System REFERENCE : DGDFA5 Development, Growth & Differentiation. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.11- 1969- Volume(issue)/page/year: 22,61,1980
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