Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,(5Z,9-alpha,11-alpha,13E,15S)-

CAS 35700-23-3 MFCD00135249

化学结构图

35700-23-3
SMILES: CCCCC[C@@](C)(O)/C=C/[C@H]1[C@H](C/C=C\CCCC(O)=O)[C@H](O)C[C@@H]1O |&1:5,10,11,21,24|

化学属性

Mol. Weight368.57
Mol. FormulaC21H36O5

别名和识别编码

CAS Number35700-23-3
Chemical NameProsta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,(5Z,9-alpha,11-alpha,13E,15S)-
Synonym 15(S)-Methylprostaglandin F2-alpha Methyl-pgf2-alpha U 32921E (5Z,9?,11?,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic Acid 15-ME-PGF2-alpha (15S)-15-Methyl-PGF2? 15(S)-15-Methyl-prostaglandin F2-alpha (15S)-15-Methylprostaglandin F2? Carboprost U 32921 (5Z,9-alpha,11-alpha,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid 15(S)-15-Methyl pgf2-alpha 15-Methylprostaglandin F2-alpha (15S)-15-Methylprostaglandin F2-alpha 15-Methyl-PGF2? Prostin 15M 15-Methylprostaglandin F2?
Beilstein Registry Number2949991
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Analog of prostaglandin F2?. Oxytocic.

相关文献及参考

  • Weeks, J.R., et al.: J. Pharmacol. Exp. Ther., 67, 186 (1973),
  • Csapo, A.I., et al.: Prostaglandins, 18, 479 (1979),
  • Schwallie, P.C., et al.: J. Reprod. Med., 23, 289 (1979),

安全信息

RTECSUK8021000 
TYPE OF TEST            : TDLo - Low

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraplacental
SPECIES OBSERVED        : Human - woman
DOSE                    : 10 ug/kg
SEX/DURATION            : female 13 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   JOGBAS Journal of Obstetrics and Gynaecology of the British Commonwealth.
   (London, UK)  V.68-81, 1961-74.  For publisher information, see BJOGAS.
   Volume(issue)/page/year: 79,737,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - woman
DOSE                    : 12 ug/kg
SEX/DURATION            : female 30 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   PRGLBA Prostaglandins.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1972-  Volume(issue)/page/year: 14,785,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - woman
DOSE                    : 5 ug/kg
SEX/DURATION            : female 14 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   JOGBAS Journal of Obstetrics and Gynaecology of the British Commonwealth.
   (London, UK)  V.68-81, 1961-74.  For publisher information, see BJOGAS.
   Volume(issue)/page/year: 79,737,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Human - woman
DOSE                    : 60 ug/kg
SEX/DURATION            : female 42 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 21,273,1980

系列性分类

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