Acetarsol sodium

CAS 5892-48-8 MFCD01664610

化学结构图

5892-48-8
SMILES: NC(=O)Nc1cc([As](=O)([O-])O)ccc1O.[Na+]

化学属性

Mol. FormulaC8H9AsNO5.Na
Mol. Weight297.09

别名和识别编码

Chemical NameSodium acetarsone
InChIKeyUYQUMYMLNDDPIP-UHFFFAOYSA-M
Synonym Arsonic acid, (3-(acetylamino)-4-hydroxyphenyl)-, monosodium salt Sodium acetarsone Sodium N-acetyl-4-hydroxy-m-arsanilate
Wiswesser Line NotationQ-AS-QO&R DQ CMV1 &-NA-
CAS Number5892-48-8
PubChem Substance ID23668632
InChIInChI=1S/C8H10AsNO5.Na/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12;/h2-4,12H,1H3,(H,10,11)(H2,13,14,15);/q;+1/p-1
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安全信息

RTECSCF8750000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 29,125,1931

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADSYAF Archives of Dermatology and Syphilology.  (Chicago, IL)  V.1-62,
   1920-50.  For publisher information, see ARDEAC.  Volume(issue)/page/year:
   25,799,1932

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADSYAF Archives of Dermatology and Syphilology.  (Chicago, IL)  V.1-62,
   1920-50.  For publisher information, see ARDEAC.  Volume(issue)/page/year:
   25,799,1932

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-

系列性分类

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