1-PHENETHYL-4-HYDROXYSALICYLAMIDO-4-METHYLPIPERIDINE HYDROCHLORIDE

CAS 25552-58-3 MFCD01667468

化学结构图

25552-58-3
SMILES: Cl.OC1C=CC=CC=1C(=O)NCC1(O)CCN(CCC2C=CC=CC=2)CC1

化学属性

Mol. FormulaC21H26N2O3.ClH
Mol. Weight390.95

别名和识别编码

Chemical NameBenzamide,2-hydroxy-N-((4-hydroxy-1-phenethyl-4-piperidinyl)methyl)-, monohydrochloride
Synonym 2-Hydroxy-N-((4-hydroxy-1-phenethyl-4-piperidinyl)methyl)benzamide
CAS Number25552-58-3
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安全信息

RTECSCV5376200
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,516,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 157 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - irritability
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,516,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 251 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - irritability
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,516,1976

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 26,516,1976

系列性分类


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