1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, phenyl ether,hydrochloride

CAS 16487-37-9 MFCD01677359

化学结构图

16487-37-9
SMILES: Cl.CN1[C@@H]2C[C@H](C[C@H]1CC2)OC1C=CC=CC=1 |&1:3,5,7|

化学属性

Mol. FormulaC14H19NO.ClH
Mol. Weight253.80

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, phenyl ether,hydrochloride
Wiswesser Line NotationT56 A ANTJ A1 GOR &GH
Synonym Tropine-3-beta-phenyl ether hydrochloride NK-1145 hydrochloride
CAS Number16487-37-9
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安全信息

RTECSYM6000000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17500 ug/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 78 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

系列性分类

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