Lucanthone Hydrochloride 盐酸硫坎酮

CAS 548-57-2 MFCD01679793

化学结构图

548-57-2
SMILES: CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12.Cl

化学属性

Mol. FormulaC20H24N2OS.ClH
Mol. Weight376.98

别名和识别编码

Chemical NameLucanthone Hydrochloride
CAS Number548-57-2
Synonym Ms. 752 Scapuren DR-15771 79T61 CBC 900139 Nilodin BW 57-233 Lucanthone monohydrochloride Tixantone 1-(beta-Diethylaminoethylamino)-4-methylthiaxanthone hydrochloride 1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one Hydrochloride Lucanthone hydrochloride 3735 R.P. Schistosomicide Miracil D Thioxanthen-9-one, 1-((2-diethylaminoethyl)amino)-4-methyl-, 1-(2-Diethylaminoethylamino)-4-methylthiaxanthone hydrochloride Lucanthone MonoHydrochloride 1-((2-Diethylaminoethyl)amino)-4-methylthioxanthen-9-one hydrochloride Miracol NSC 14574 1-Diaethylamino-aethylamino-4-methyl-thioxanthonhydrochlorid NIH 3127 RP 3735
Chemical Name Translation盐酸硫坎酮
Wiswesser Line NotationT C666 BS IVJ D1 GM2N2&2 &GH
PubChem Substance ID11054
InChIInChI=1S/C20H24N2OS.ClH/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20;/h6-11,21H,4-5,12-13H2,1-3H3;1H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Anthelmintic (Schistosoma).

相关文献及参考

  • Galitski, T., et al.: Science, 285, 251 (1999),
  • Bubb, M., et al.: J. Biol. Chem., 269, 14869 (1994),
  • Duncan, K., et al.: Biochem. Pharmacol., 52, 1553 (1996),

安全信息

RTECSXO1605800 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   20,31,1947

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 181 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   20,31,1947

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Neurospora crassa
DOSE/DURATION           : 75 mg/L/2H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 55,43,1978

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 2600 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 82,111,1981

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   ACIEAY Angewandte Chemie, International Edition in English.  (VCH Pub.,
   Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441)  V.1-    1962-
   Volume(issue)/page/year: 10,302,1971

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 2200 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 82,111,1981

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 5 umol/L
REFERENCE :
   ZENBAX Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie,
   Organische Chemie, Biochemie, Biophysik, Biologie.  (Tuebingen, Fed. Rep.
   Ger.)  V.2B-27B, 1947-1972.

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 10 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub

系列性分类

相关产品推荐