4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,6-((aminophenylacetyl)amino)- 3,3-dimethyl-7-oxo-,1,3-dihydro-3-oxo-1-isobenzofuranyl ester,monohydrochloride,(2S-(2-alpha,5-alpha,6-beta-(S*)))-

CAS 39878-70-1 MFCD01682149

化学结构图

39878-70-1
SMILES: Cl.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3C=CC=CC=3)C(=O)N2[C@H]1C(=O)OC1OC(=O)C2C=CC=CC=21

化学属性

Mol. FormulaC24H23N3O6S.ClH
Mol. Weight518.02

别名和识别编码

Chemical Name4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,6-((aminophenylacetyl)amino)- 3,3-dimethyl-7-oxo-,1,3-dihydro-3-oxo-1-isobenzofuranyl ester,monohydrochloride,(2S-(2-alpha,5-alpha,6-beta-(S*)))-
Wiswesser Line NotationT56 BVO DHJ DOV- GT45 ANV ESTJ CMVYZR& F1 F1 &GH
Synonym Talampicillin hydrochloride PC 183 Yamacillin
CAS Number39878-70-1
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安全信息

RTECSXH8430000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 786 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,441,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,441,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,441,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,441,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo

系列性分类

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