Pyrido(2,3-d)pyrimidine, 2,4-diamino-6-sec-butyl-5-methyl-

CAS 7319-47-3 MFCD01690122

化学结构图

7319-47-3
SMILES: CCC(C)c1cnc2nc(N)nc(N)c2c1C

化学属性

Mol. FormulaC12H17N5
Mol. Weight231.34

别名和识别编码

Chemical NamePyrido(2,3-d)pyrimidine, 2,4-diamino-6-sec-butyl-5-methyl-
Wiswesser Line NotationT66 BN DN JNJ CZ EZ G1 HY2&1
Synonym BW 58-283 BW 283U 2,4-Diamino-5-methyl-6-sec-butylpyrido(2,3-d)pyrimidine 2,4-Diamino-5-methyl-6-(but-2-yl)pyrido(2,3-d)pyrimidine BW 58-283b Pyrido(2,3-d)pyrimidine-2,4-diamine, 5-methyl-6-(1-methylpropyl)-
Beilstein Registry Number0614824
CAS Number7319-47-3
InChIKeyHKBUPBPYXKXWBQ-UHFFFAOYSA-N
PubChem Substance ID134640
InChIInChI=1S/C12H17N5/c1-4-6(2)8-5-15-11-9(7(8)3)10(13)16-12(14)17-11/h5-6H,4H2,1-3H3,(H4,13,14,15,16,17)
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安全信息

RTECSUV1155900
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   14XBAV "International Congress of Chemotherapy, Proceedings of the 3rd
   Congress, 1963," Kuemmerle, H.P., and Prezios, P., Stuttgart, Fed. Rep.
   Ger., Georg Thieme Verlag, 1964  Volume(issue)/page/year: -,367,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,711,1968

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 11 nmol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   25,1947,1976

系列性分类


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