Pizotifen malate 4-(9,10-二氢-4H-苯并[4,5]环庚[1,2-b]噻吩-4-亚基)-1-甲基哌啶-2-羟基琥珀酸盐
CAS 5189-11-7 MFCD00798251
化学结构图
SMILES: CN1CCC(=C2c3ccccc3CCc3sccc32)CC1.O=C(O)/C=C\C(=O)O
化学属性
| Mol. Formula | C19H21NS.C4H4O4 |
|---|---|
| Mol. Weight | 411.52 |
别名和识别编码
| Chemical Name | Pizotifen malate |
|---|---|
| Chemical Name Translation | 4-(9,10-二氢-4H-苯并[4,5]环庚[1,2-b]噻吩-4-亚基)-1-甲基哌啶-2-羟基琥珀酸盐 |
| PubChem Substance ID | 168993 |
| InChI | InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,1H2,(H,6,7)(H,8,9) |
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相关文献及参考
- [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026.
- [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.
- [1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52.
- [1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52.
- [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026.
- [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.
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