Phosphonic acid,((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxymethylene)bis-

CAS 106871-13-0 MFCD01706360

化学结构图

106871-13-0
SMILES: CC1C=CC(=CC=1N(CCCl)CCCl)C(O)(P(O)(O)=O)P(O)(O)=O

化学属性

Mol. FormulaC12H19Cl2NO7P2
Mol. Weight422.16

别名和识别编码

Chemical NamePhosphonic acid,((3-(bis(2-chloroethyl)amino)-4-methylphenyl)hydroxymethylene)bis-
Synonym 3-(Bis(2-chloroethyl)amino)-4-methylphenyl-hydroxymethanbiphosphonic acid
CAS Number106871-13-0
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安全信息

RTECSSZ6790000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 88 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 1250 ug/plate
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1250 ug/tube
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 6,67,1988

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