2H-1,3,2-Oxazaphosphorin-2-amine,N-(2-chloroethyl)tetrahydro-, 2-oxide

CAS 36761-83-8 MFCD01710217

化学结构图

36761-83-8
SMILES: O=P1(NCCCl)NCCCO1

化学属性

Mol. FormulaC5H12ClN2O2P
Mol. Weight198.61

别名和识别编码

Chemical Name2H-1,3,2-Oxazaphosphorin-2-amine,N-(2-chloroethyl)tetrahydro-, 2-oxide
CAS Number36761-83-8
Synonym Dechloroethylcyclophosphamide Dechloroethylcyclophosph Monochloroethylcyclophosphamide ASTA 4968 Asta 4968 N-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide N-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 2-(2-Chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide 3-Dechloroethylifosfamide N-Dechloroethylcyclophosphamide
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分类

  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Phosphorylating and Phosphitylating Agents,

产品应用

  • A metabolite of Cyclophosphamide (C988580).

相关文献及参考

  • Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996),
  • Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997),
  • Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),

安全信息

RTECSRP5788670 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Bird - chicken Cells - not otherwise specified
DOSE/DURATION           : 70 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 268,115,1992

系列性分类

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