2-Imidazoline,2-((2-chloro-4-methyl-3-thienyl)amino)-,monohydrochloride

CAS 51274-83-0 MFCD01720884

化学结构图

51274-83-0
SMILES: Cl.CC1=CSC(Cl)=C1NC1NCCN=1

化学属性

Mol. FormulaC8H10ClN3S.ClH
Mol. Weight252.18

别名和识别编码

Chemical Name2-Imidazoline,2-((2-chloro-4-methyl-3-thienyl)amino)-,monohydrochloride
Synonym 2-(2'-Chloro-4'-methyl-3'-thienylamino)-1,3-diazacyclo-pent-2-ene
Wiswesser Line NotationT5SJ BG D1 CM- BT5M CN BUTJ &GH
CAS Number51274-83-0
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安全信息

RTECSNJ2465000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Autonomic Nervous System - sympathomimetic
   Skin and Appendages - hair
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 211,305,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Autonomic Nervous System - sympathomimetic
   Skin and Appendages - hair
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 211,305,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Autonomic Nervous System - sympathomimetic
   Skin and Appendages - hair
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 211,305,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses

系列性分类

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