Nibufin

CAS 1224-64-2 MFCD01741580

化学结构图

1224-64-2
SMILES: CCCCP(=O)(CCCC)Oc1ccc([N+](=O)[O-])cc1

化学属性

Mol. FormulaC14H22NO4P
Mol. Weight299.34

别名和识别编码

Chemical NameNibufin
InChIKeyMQOMKCIKNDDXEZ-UHFFFAOYSA-N
Synonym 4-nitrophenyl dibutylphosphinic acid Dibutyl-phosphinic acid, 4-nitrophenyl ester Nibufin Nibuphin Tarin nibufin p-Nitropenylester kyseliny dibutylfosfinove p-Nitrophenyldi-n-butylphosphinate p-Nitrophenyldibutylphosphinate p-nitrophenyl di-N-butylphosphinate p-nitrophenyl dibutylphosphinic acid
Wiswesser Line NotationWNR DOPO&4&4
CAS Number1224-64-2
Beilstein Registry Number2509364
PubChem Substance ID71041
InChIInChI=1S/C14H22NO4P/c1-3-5-11-20(18,12-6-4-2)19-14-9-7-13(8-10-14)15(16)17/h7-10H,3-6,11-12H2,1-2H3
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安全信息

RTECSSZ4600000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7200 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - bronchiolar constriction
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 42,299,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   49,23,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 560 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   49,23,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 42,106,1979

TYPE OF T

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