Bleomycinamide, N(sup1)-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-

CAS 37293-17-7 MFCD01751489

化学结构图

37293-17-7
SMILES: CC1C(=NC(=NC=1N)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)C(=O)N[C@@H]([C@@H](O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)C1=CNC=N1)C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC1=NC(=CS1)C1=NC(=CS1)C(=O)NCCCNCCCCNCCCN

化学属性

Mol. FormulaC60H96N20O21S2
Mol. Weight1497.88

别名和识别编码

Chemical NameBleomycinamide, N(sup1)-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-
Synonym N(sup 1)-(3-((4-((3-Aminopropyl)amino)butyl)amino)propyl)bleomycinamide Bleomycin A6 Boanmycin
CAS Number37293-17-7
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安全信息

RTECSEC5991325 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 97780 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZKZAEY Zhongguo Kangshengsu Zazhi.  Chinese Journal of Antibiotics.
   (Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
   Rep. China)  V.13-    1988-  Volume(issue)/page/year: 15,453,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70530 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZKZAEY Zhongguo Kangshengsu Zazhi.  Chinese Journal of Antibiotics.
   (Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
   Rep. China)  V.13-    1988-  Volume(issue)/page/year: 15,453,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80330 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZKZAEY Zhongguo Kangshengsu Zazhi.  Chinese Journal of Antibiotics.
   (Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
   Rep. China)  V.13-    1988-  Volume(issue)/page/year: 15,453,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZKZAEY Zhongguo Kangshengsu Zazhi.  Chinese Journal of Antibiotics.
   (Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu,

系列性分类

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