Ramoplanin 雷莫拉宁

CAS 76168-82-6 MFCD01775776

化学结构图

76168-82-6
SMILES: CC(C)C[C@H](NC(=O)CNC(=O)C(NC(=O)[C@@H](NC(=O)C(NC(=O)[C@@H](CCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H](CCCN)NC(=O)[C@H](NC(=O)C(CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)/C=C\C=C/CCC)C1CCC(O)CC1)[C@H](C)O)C1CCC(O)CC1)C1CCC(O)CC1)[C@H](C)O)C1CCC(O)CC1)[C@H](C)O)C1CCC(O)CC1)C(=O)N[C@H](C)C(=O)NC(C1CC(Cl)C(O)CC1)C(O)=O

别名和识别编码

Synonym A 16686 A 16686 Antibiotic A 16686 Antibiotic A 16686 MDL 62198 Ramoplanin
MDL NumberMFCD01775776
Chemical NameRamoplanin
InChIKeyFSBZBQUUCNYWOK-YIOPJBSBSA-N
CAS Number76168-82-6
Chemical Name Translation雷莫拉宁
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分类

  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class, Glycopeptides, Interferes with Cell Wall Synthesis, L - Z, Mechanism of Action, Spectrum of Activity
  • {SNA} Antibacterial, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class, Glycopeptides, Interferes with Cell Wall Synthesis, L - Z, Mechanism of Action, Spectrum of Activity, 抗生素, 生化试剂

安全信息

GHS Symbol
WGK Germanynwg
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H318 Causes serious eye damage 严重伤害眼睛
RTECSVE5050000
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
Hazard Codes Xi
Risk Statements
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,318,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 122 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,318,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #81-97237

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Mechanism of Action - Antibiotics
  4. Interferes with Cell Wall Synthesis - Mechanism of Action

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