Bepotastine besilate 苯磺酸贝托司汀

CAS 190786-44-8 MFCD01938491

化学结构图

190786-44-8
SMILES: OC(=O)CCCN1CCC(CC1)O[C@@H](C1=CC=C(Cl)C=C1)C1=CC=CC=N1.OS(=O)(=O)C1C=CC=CC=1

化学属性

Mol. FormulaC27H31ClN2O6S
Mol. Weight547.06

别名和识别编码

Chemical NameBepotastine besilate
CAS Number190786-44-8
Synonym ########
Chemical Name Translation苯磺酸贝托司汀
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分类

  • Amino Acids & Derivatives
  • Aromatics
  • Drug Analogues
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Bepotastine is a histamine H1 receptor anatagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions

相关文献及参考

  • [2]. Tsugunobu Andoh, et al. Suppression by bepotastine besilate of substance P-induced itch-associated responses through the inhibition of the leukotriene B4 action in mice. Eur J Pharmacol. 2006 Oct 10;547(1-3):59-64.
  • Kaminuma, O. et al.: Biol. Pharm. Bull., 21, 411 (1998); Kitaba, S. et al.: J. Allergy, No pp. given (2008); Lyseng-Williamson, K.A., Drugs, 70, 1579 (2010);
  • [1]. Jon I Williams, et al. Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate. Curr Med Res Opin. 2010 Oct;26(10):2329-38.
  • [1]. Jon I Williams, et al. Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate. Curr Med Res Opin. 2010 Oct;26(10):2329-38.
  • [2]. Tsugunobu Andoh, et al. Suppression by bepotastine besilate of substance P-induced itch-associated responses through the inhibition of the leukotriene B4 action in mice. Eur J Pharmacol. 2006 Oct 10;547(1-3):59-64.

系列性分类


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