1,4-Dichloro-2,3-epoxybutane

CAS 3583-47-9 MFCD00233691

化学结构图

3583-47-9
SMILES: ClCC1OC1CCl

化学属性

Mol. FormulaC4H6Cl2O
Mol. Weight141.00

别名和识别编码

Chemical NameButane, 1,4-dichloro-2,3-epoxy-
Wiswesser Line NotationT3OTJ B1G C1G
Synonym 1,4-Dichloro-2,3-epoxybutane 1,4-Dichlorobutene-2,3-epoxide 1,4-dichloro-2,3-epoxybutane
CAS Number3583-47-9
Beilstein Registry Number0103237
PubChem Substance ID19160
InChIInChI=1S/C4H6Cl2O/c5-1-3-4(2-6)7-3/h3-4H,1-2H2
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安全信息

RTECSEJ8050000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2830 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   41,249,1979

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Klebsiella pneumoniae
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,269,1981

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 3600 umol/L/3D (Intermittent)
REFERENCE :
   35WYAM "In Vitro Metabolic Activation in Mutagenic Testing, Proceedings of
   the Symposium, Research Triangle Park, NC, 1976," De Serres, F.J., et al.,
   eds., New York, Elsevier Science Pub. Co., Inc., 1976
   Volume(issue)/page/year: -,63,1976

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